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目錄:珀金埃爾默企業(yè)管理(上海)有限公司>> AequoZen FroZen cells, Serotonin 5-HT3A, Human Recombinant, HEK293

AequoZen FroZen cells, Serotonin 5-HT3A, Human Recombinant, HEK293
  • AequoZen FroZen cells, Serotonin 5-HT3A, Human Recombinant, HEK293
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更新時(shí)間:2025-03-04 18:04:37瀏覽次數(shù):88評(píng)價(jià)

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Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazin......

Frozen Cells validated for calcium testing: Serotonin 5-HT3A channel, human recombinant, in HEK293 host cell. We provide one vial of frozen cells (10 million cells/vial). Some of our Frozen cells may be restricted for sale in specified countries. Please inquire at your local sales office for more information. You are authorized to utilize these frozen cell preparations one time only. Any attempt to transfer, re-use, or propagate these cells is expressly unauthorized and a violation of the product terms and conditions of sale.

Features:

  • Pre-validated batches of ready-to-use cells for calcium testing
  • Optimized to alleviate biological variability
  • Step-by-Step protocols for culture-free functional testing on our validated cells
  • Affordable access to small aliquots of cells (minimum size: 10 million cells/vial)
  • Ready-to-use cells for Profiling, Pharmacology or Screening applications
  • Up-scaling and customized developments

The AequoScreen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.

The frozen cells approach to functional testing consists in the dissociation of cell culture from testing. That means that we will culture the cells and freeze them with an optimized protocol to stop all replication. These cells are then stored in liquid nitrogen or simply in a -80°C freezer, thawed and used directly in a functional, cellular GPCR test with previously validated performance.

規(guī)格

檢測目標(biāo)類Ion channel
檢測目標(biāo)類型Cell line
檢測驗(yàn)證Calcium Luminescence
宿主細(xì)胞HEK293
產(chǎn)品品牌名稱AequoZen
包裝量18.0 Million Cells
受體類型5-Hydroxytryptamine (Serotonin)
第二信使釋放Calcium flux
運(yùn)輸條件干冰
治療領(lǐng)域Central Nervous System
產(chǎn)品尺寸1 vial

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